Some of the most important European names in the field of furniture design contributed to the interior of Casa de Serralves: Ruhlmann, René Lalique (1880−1945), Edgar Brandt (1880−1960), Ivan da Silva Bruhns (1881−1980), Jules Leleu (1883−1961), Jean Perzel (1892−1986) and Raymond Subes (1893−1970).

Carlos Alberto and his wife Blanche Daubin were to settle in the House in 1944, however they lived there for a few years. In 1955, the property was sold to Delfim Ferreira (1888−1960), on condition that the property was not subject to any transformation. The commitment was fully respected. Much of the furniture was sold at auctions, and is now dispersed.